| 发明名称 |
Pharmacokinetic and pharmacodynamic modeling of erythropoietin administration. |
| 摘要 |
The present invention relates to systems and methods for obtaining optimized EPO dosage regimens for a desired pharmacodynamic/pharmacokinetic response. The system includes choosing one or more EPO dosage regimens, then using a PK/PD model to determine the pharmacodynamic/pharmacokinetic profile of one or more EPO dosage regimens, and finally selecting one of the EPO dosage regimens for administration to achieve the desired pharmacodynamic/pharmacodynamic response based on the EPO profile. |
| 申请公布号 |
ZA200109527(B) |
申请公布日期 |
2003.10.20 |
| 申请号 |
ZA20010009527 |
申请日期 |
2001.11.19 |
| 申请人 |
ORTHO-MCNEIL PHARMACEUTICALS, INC. |
发明人 |
WING CHEUNG;CHRISTINE COTE;DAVID GIBSON;ELS VERCAMMEN |
| 分类号 |
A61K38/00;A61K31/282;A61K31/7072;A61K33/24;A61K38/12;A61K38/18;A61K38/22;A61M37/00;A61P7/00;A61P7/06;A61P7/08;A61P13/12;A61P19/02;A61P29/00;A61P31/18;A61P35/00;A61P43/00;G06F19/00;G06Q10/00 |
主分类号 |
A61K38/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
