CLOSED SUBSTRATE PLATFORMS SUITABLE FOR ANALYSIS OF BIOMOLECULES

摘要

The invention relates to a closed substrate platform comprising: a container comprising an area for sample analysis and a microfluidic analysis platform, the container comprising (i) at least one inlet for the introduction of fluid to the sample analysis area and (ii) an outlet for removal of fluid to the sample analysis area; and a vent for expulsion of air from the container. The substrate platform may be used for covalent immobilization of polypeptides and nucleic acids and may be used in conjunction with any type of equipment typically used to manipulate or evaluate a standard microscope slide, such as a scanner.