Aspects of the present invention include probes, methods, systems that have stand alone utility and may comprise features of a drug discovery system or method. The present invention also includes pharmaceutical compositions. In more detail, the present invention provides molecular probes and methods for producing molecular probes. The present invention provides also provides systems and methods for new drug discovery. An embodiment of the present invention utilizes sets of probes of the present invention and a new approach to computational chemistry in a drug discovery method having increased focus in comparison to heretofore utilized combinatorial chemistry. The present invention also provides computer software and hardware tools useful in drug discovery systems. In an embodiment of a drug discovery method of the present invention in silico methods and in biologico screening methods are both utilized to maximize the probability of success while minimizing the time and number of wet laboratory steps necessary to achieve the success.
申请公布号
WO03084997(A1)
申请公布日期
2003.10.16
申请号
WO2002US11624
申请日期
2002.04.10
申请人
TRANSTECH PHARMA, INC.;MJALLI, ADNAN, M., M.;ANDREWS, ROBERT;BAUDRY, JEROME;YOKUM, SCOTT;BANNER, WILLIAM;WYSONG, CHRISTOPHER
发明人
MJALLI, ADNAN, M., M.;ANDREWS, ROBERT;BAUDRY, JEROME;YOKUM, SCOTT;BANNER, WILLIAM;WYSONG, CHRISTOPHER