发明名称 |
(3Z) -3-(3-HYDRO-ISOBENZOFURAN-1-YLIDENE)-1, 3-DIHYDRO-2H-INDOL-2-ONES AS KINASE INHIBITORS |
摘要 |
The present invention relates to organic molecules represented by the genera l formula (I) wherein: X is O; Y is [C(R2)2]c;. R, R1, R2,-a, b and c are as disclosed in the description; and pharmaceutically acceptable salts thereof, capable of modulating tyrosine kings signal transduction in order to regulat e, modulate and/or inhibit abnormal cell proliferation.
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申请公布号 |
CA2481036(A1) |
申请公布日期 |
2003.10.16 |
申请号 |
CA20032481036 |
申请日期 |
2003.04.02 |
申请人 |
ALLERGAN, INC. |
发明人 |
WANG, SHIMIAO;MALONE, THOMAS;GUO, XIALING;ZHU, ZHEN;WURSTER, JULIE A.;HULL, CLARENCE E., III;ANDREWS, STEVEN W.;WANG, EDWARD H. |
分类号 |
A61K31/404;A61K31/454;A61K31/496;A61K31/5377;A61K31/541;A61P1/16;A61P3/10;A61P7/02;A61P9/10;A61P13/12;A61P17/02;A61P17/06;A61P19/02;A61P25/28;A61P27/02;A61P29/00;A61P35/00;A61P37/06;A61P43/00;C07D405/04;C07D405/14;C07D413/14;C07D491/10;(IPC1-7):C07D491/107;C07D417/14 |
主分类号 |
A61K31/404 |
代理机构 |
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