| 摘要 |
The invention relates to an improved method for producing 2,2-dichloro or dibromo-phenyl alkyl acetates of formula (1), in which X represents Cl or Br , n represents a whole number from 1 to 5, R represents hydrogen, C1-C8 alkyl, aryl, heteroaryl, C1-C8 alkoxy, aryloxy or halogen and R1 represents C1-C8 alkyl. According to said method, a 2,2-dichloro- or dibromo-phenylacetonitri le of formula (II) is reacted in 0.8 to 2 mol water per mol nitrile of formula (II), 1 to 8 mol alcohol of formula R1OH (III) per mol nitrile of formula (I I) and in the presence of 1 to 3 mol HCl or HBr per mol nitrile of formula (II) , optionally in the presence of a solvent that is inert in the reaction conditions, to form the corresponding 2,2-dichloro- or dibromo-phenyl alkyl acetates of formula (I), whereby the reaction temperature in the first phase lies between 30 and 60 ~C and in the second phase between 60 and 100 ~C. Onc e the reaction has taken place, the reaction mixture is cooled to between 20 a nd 40 ~C, diluted with water and the 2,2-dichloro- or dibromo-phenyl alkyl acetate of formula (I) is isolated.
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