发明名称 |
PROCESS FOR PRODUCING MODIFIED PEPTIDE |
摘要 |
A process for producing a peptide or a protein containing an amino acid residue having a modified side chain characterized by comprising chemically producing a peptide fragment containing an amino acid residue having a modified side chain with the use of a weakly acidic eliminating resin, producing by a genetic modification method and/or an enzymatic method another peptide fragment containing no amino acid residue having a modified side chain, and then fusing the obtained two peptides fragments with each other. According to this process, a peptide or a protein having a modification such as acylation, glycosylation or phosphorylation and being excellent in qualities can be efficiently obtained.
|
申请公布号 |
WO03084983(A1) |
申请公布日期 |
2003.10.16 |
申请号 |
WO2003JP04590 |
申请日期 |
2003.04.10 |
申请人 |
DAIICHI SUNTORY PHARMA CO., LTD.;KANGAWA, KENJI;MINAMITAKE, YOSHIHARU;MATSUMOTO, MASARU;MAKINO, TOMOHIRO |
发明人 |
MINAMITAKE, YOSHIHARU;MATSUMOTO, MASARU;MAKINO, TOMOHIRO |
分类号 |
C07K1/04;C07K1/107;C07K9/00;C07K14/46;C07K14/465;C07K14/60;(IPC1-7):C07K1/04;C07K1/06 |
主分类号 |
C07K1/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|