发明名称 Indolyl-3-glyoxylic acid derivatives having antitumor action
摘要 The invention relates to the use of N-substituted indole-3-glyoxylamides of the general formula I as antitumor agents and to a pharmaceutical composition having antitumor action, characterized in that it contains at least one of the compounds of the general formula 1, if appropriate also in the form of the physiologically tolerable acid addition salts or N-oxides. Furthermore, the invention also includes antitumor agents comprising as active compound one or more N-substituted indole-3-glyoxylamides according to the general formula 1 and, if appropriate, their physiologically tolerable acid addition salts and, if possible, N-oxides and a pharmaceutically utilizable carrier and/or diluent or auxiliary substance in the form of tablets, coated tablets, capsules, solutions for infusion or ampoules, suppositories, patches, powder preparations which can be employed by inhalation, suspensions, creams and ointments.
申请公布号 US2003195360(A1) 申请公布日期 2003.10.16
申请号 US20020309204 申请日期 2002.12.04
申请人 发明人 NICKEL BERND;SZELENYI ISTVAN;SCHMIDT JURGEN;EMIG PETER;REICHERT DIETMAR;GUNTHER ECKHARD;BRUNE KAY;LE BAUT GUILLAUME
分类号 C07D401/06;A61K31/403;A61K31/404;A61K31/4178;A61K31/4427;A61K31/4439;A61K31/444;A61K31/454;A61K31/4545;A61K31/4709;A61K31/496;A61P35/00;A61P35/02;A61P35/04;C07D209/18;C07D401/12;C07D401/14;(IPC1-7):C0743/14;C0743/02 主分类号 C07D401/06
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