摘要 |
The protein derivatives have the general formula <IMAGE> in which n is a number from 1 to 3, A is the residue of a protein of the lectin or bacteriotoxin type, R1 is a residue of a carbohydrate from the group comprising mono-, di-, tri- and tetrasaccharides and derivatives thereof, and R2 is a hydrogen atom, a C1-C10-alkyl radical or the nitro group, and suppress binding of lectins or bacteriotoxins to the cell surface; compounds suitable for inactivating proteins and processes for preparing these protein derivatives and compounds, and the use of the inactive protein derivatives for preparing immunotoxins are described. |