发明名称 PROTEIN DERIVATIVE AND ITS PRODUCTION
摘要 The protein derivatives have the general formula <IMAGE> in which n is a number from 1 to 3, A is the residue of a protein of the lectin or bacteriotoxin type, R1 is a residue of a carbohydrate from the group comprising mono-, di-, tri- and tetrasaccharides and derivatives thereof, and R2 is a hydrogen atom, a C1-C10-alkyl radical or the nitro group, and suppress binding of lectins or bacteriotoxins to the cell surface; compounds suitable for inactivating proteins and processes for preparing these protein derivatives and compounds, and the use of the inactive protein derivatives for preparing immunotoxins are described.
申请公布号 JPS62169800(A) 申请公布日期 1987.07.25
申请号 JP19870005217 申请日期 1987.01.14
申请人 EEBEBUE ARZNEIMITTEL GMBH 发明人 FURIIDORITSUHI HIREBURANTO;HARARUTO MISHIYAKU
分类号 C07K14/195;A61K35/74;A61K36/18;A61K38/00;A61K38/36;A61K39/00;A61K47/48;C07H13/08;C07K1/107;C07K1/113;C07K14/00;C07K14/41;C07K14/415;C07K14/42 主分类号 C07K14/195
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