| 摘要 |
The object of the present invention is to provide a composition for the prophylaxis or treatment of hepatopathy. ÄSolutionÜ <??>A composition containing as an active ingredient a compound of formula (I), or a pharmacologically acceptable salt, ester or other derivative thereof for the prophylaxis or treatment of hepatopathy: <CHEM> Äwherein: A is a pyrrole ring; R<1> is an optionally substituted aryl or heteroaryl group; R<2> is an optionally substituted heteroaryl group; R<3> represents a group of the formula -X-R<4>, wherein X is a single bond or an optionally substituted alkylene, alkenylene or alkynylene group, and R<4> is a substituted cycloalkyl group, a substituted aryl group, an optionally substituted heterocyclyl group, an optionally substituted heteroaryl group, or -NR<a>R<b>, wherein each of R<a> and R<b> is a hydrogen atom or an alkyl, alkenyl, alkynyl, aralkyl or alkylsulfonyl group; PROVIDED THAT said substituents R<1> and R<3> are bonded to the two atoms of said pyrrole ring which are adjacent to the atom of the pyrrole ring to which said substituent R<2> is bondedÜ.
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