发明名称 |
USE OF ANTI-TNF.ALPHA.ANTIBODIES AND ANOTHER DRUG |
摘要 |
The present invention is directed to a method of treating disorders in which TFN.alpha. activity is detrimental via biweekly, subcutaneous administration of human antibodies, preferably recombinant human antibodies, that specifically bind to human tum or necrosis factor a (hTNF.alpha.) in combination with another drug which is useful for treating the disorder. An antibody of the invention can be a full-length antibody or an antigen- binding portion thereof. Kits containing a pharmaceutical composition and instructions for dosing are also encompassed by the invention.
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申请公布号 |
CA2385777(A1) |
申请公布日期 |
2003.10.14 |
申请号 |
CA20022385777 |
申请日期 |
2002.05.10 |
申请人 |
ABBOTT LABORATORIES (BERMUDA) LTD. |
发明人 |
FISCHKOFF, STEVEN;CHARTASH, ELLIOT |
分类号 |
A61K45/00;A61K31/42;A61K31/4706;A61K31/519;A61K31/635;A61K39/395;A61P1/00;A61P3/10;A61P11/00;A61P13/12;A61P19/00;A61P25/00;A61P27/02;A61P29/00;A61P31/04;A61P35/00;A61P37/06;A61P37/08;C07K16/24;(IPC1-7):A61K45/08 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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