发明名称 |
Processes of purifying oligonucleotides |
摘要 |
Methods for preparing purified oligonucleotides by treating a solution comprising an oligonucleotide with an aggregating agent and a precipitation enhancer under conditions sufficient to form an oligonucleotide aggregate and isolating the oligonucleotide aggregate to produce a purified oligonucleotide.</PTEXT>
|
申请公布号 |
US6632938(B2) |
申请公布日期 |
2003.10.14 |
申请号 |
US20010876242 |
申请日期 |
2001.06.07 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
MOORE MAX N.;ARTHUR JOHN CHARLES;VANSOOY KENT;SCOZZARI ANTHONY N. |
分类号 |
C07H21/00;C12N15/10;C12Q1/68;(IPC1-7):C07H21/00;C07H21/02;C07H21/04 |
主分类号 |
C07H21/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|