The present invention relates to peptide fragments which have one or more shared and/or similar amino acid sequences to amino acid sequences of specific portions of the 14 kDa protein of S. mansoni (SM14) or related FABPs (Fatty Acid Binding Proteins), the peptide fragments functioning as continuous or discontinuous epitopic regions of the molecule or mimicking its biological activity. More particularly, the present invention relates to a method for constructing active peptide fragments, peptide fragments, immunogenic compositions and diagnostic kits using peptide fragments.
申请公布号
AU2003213900(A1)
申请公布日期
2003.10.13
申请号
AU20030213900
申请日期
2003.04.01
申请人
FUNDACAO OSWALDO CRUZ-FIOCRUZ
发明人
MIRIAM TENDLER;RICHARD, CHARLES GARRAT;NAFTALE KATZ;ANDREW, JOHN, GEORGE SIMPSON;FRANK, JEFFERSON, ALARCON DE BARRIENTOS;MONICA, MAGNO VILAR;MARILIA, SIRIANNI, DOS SANTOS ALMEIDA