| 发明名称 |
USE OF DISCOIDIN DOMAIN RECEPTOR 1 (DDR1) AND AGENTS THAT AFFECT THE DDR1/COLLAGEN PATHWAY |
| 摘要 |
<p>The disclosure provides methods of modulating the activity of DDR1. Methods for screening for agents that activate DDR1 are disclosed. Methods for inducing the maturation of immature macrophages and immature dendritic cells are also disclosed. In addition, methods for increasing neutrophil activation using a DDR1 activating agent, and methods for increasing leukocyte migration using a DDR1 activating agent, are provided.</p> |
| 申请公布号 |
AU2002361653(A1) |
申请公布日期 |
2003.10.13 |
| 申请号 |
AU20020361653 |
申请日期 |
2002.12.11 |
| 申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF |
发明人 |
TEIZO YOSHIMURA |
| 分类号 |
A61K35/14;A61K39/00;C07K14/705;C07K16/28;C12N5/0781;C12N5/0783;C12N5/0784;C12N5/0786;C12N5/0787;(IPC1-7):A61K39/00;C12N15/87;A61K39/395;A61K48/00;C07K16/00;C12N15/00;C12N15/63 |
主分类号 |
A61K35/14 |
| 代理机构 |
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