发明名称 |
PROCESS TO PREPARE EPLERENONE |
摘要 |
Novel processes for the C-17 spirolactonization and 6,7 oxidation of steroid compounds are provided. In certain preferred embodiments, the present invention provides for the preparation of steroid compounds which are useful in the preparation of methyl hydrogen 9,11alpha-epoxy-17alpha-hydroxy-3-oxopregn-4-ene-7alpha,21-dicarboxylate, gamma-lactone (otherwise referred to as eplerenone or epoxymexrenone). |
申请公布号 |
AU2003259022(A1) |
申请公布日期 |
2003.10.13 |
申请号 |
AU20030259022 |
申请日期 |
2003.03.21 |
申请人 |
PHARMACIA AND UPJOHN COMPANY |
发明人 |
BRUCE, ALLEN PEARLMAN;AMPHLETT, GREG PADILLA;JEFFREY, L. HAVENS;SONJA, S. MACKEY;HAIFENG WU |
分类号 |
C07J21/00;C07C41/50;C07C43/305;C07J1/00;C07J71/00;(IPC1-7):C07J1/00 |
主分类号 |
C07J21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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