| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide an optical waveguide type protein chip capable of both shortening a reaction time between proteins in a specimen solution such as blood and an antibody and highly sensitively detecting protein molecules even through the use of the specimen solution of a very small quantity. <P>SOLUTION: The optical waveguide type protein chip is provided with a substrate, a first optical waveguide layer formed on the surface of the substrate, gratings each formed on the surfaces of both end parts of the first optical waveguide layer, a second optical waveguide layer made of a transparent conductive material having a refractive index higher than that of the first optical waveguide layer and formed on the first, optical waveguide layer located between the gratings, an antibody fixing film formed on the second optical waveguide layer, a first insulating member formed on the substrate containing the first optical waveguide layer and having a recessed well at a part at which the antibody immobilizing film is located, and an electrode membrane formed in such a way that its part is close to the well on the first insulating member for generating electric charge in-between the second optical waveguide layer. <P>COPYRIGHT: (C)2004,JPO |
