摘要 |
<p>The present invention relates to certain substituted sulfamic acids, which exhibit inhibitory action against Human Cytoplasmic Protein Tyrosine Phosphatases (HC-PTPs, Low Molecular Weight Protein Tyrosine Phosphatases, Orthophosphoric Monoester Phosphohydrolase; EC: 3.1.3.2). These compounds are indicated in the treatment or management of wounds and diseased tissues by acceleration of wound repair. The present invention also includes within its scope methods for the treatment of wounds by the administration of the aforesaid sulfamic acids as well as pharmaceutical compositions thereof. This invention relates to active pharmaceutical compositions that facilitate the healing of wounds and repair of tissue, and methods of making and using them. These pharmaceutical compositions, which are sulfamic acids and related compounds, inhibit Human Cytoplasmic Protein Tyrosine Phosphatases, an enzyme that impedes angiogenesis.</p> |