| 发明名称 |
SUBSTITUTED BENZAZOLES AND USE THEREOF AS RAF KINASE INHIBITORS |
| 摘要 |
New substituted benz-azole compounds of formula (I), compositions and method s of inhibition of Raf kinase activity in a human or animal subject are provided. The new compounds compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.
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| 申请公布号 |
CA2480638(A1) |
申请公布日期 |
2003.10.09 |
| 申请号 |
CA20032480638 |
申请日期 |
2003.03.31 |
| 申请人 |
CHIRON CORPORATION |
发明人 |
RAMURTHY, SAVITHRI;RENHOWE, PAUL A.;SUNG, LEONARD;FANTL, WENDY;AMIRI, PAYMAN;LEVINE, BARRY HASKELL;POON, DANIEL J.;SUBRAMANIAN, SHARADHA |
| 分类号 |
A61K31/4439;A61K31/444;A61K31/4545;A61K31/46;A61K31/4725;A61K31/496;A61K31/506;A61K31/5377;A61K31/55;A61K31/551;A61K45/00;A61P35/00;A61P43/00;C07D401/12;C07D401/14;C07D405/12;C07D405/14;C07D409/14;C07D413/04;C07D413/12;C07D413/14;C07D417/12;C07D417/14;C07D451/14;C07D453/02;(IPC1-7):C07D453/02;C07D401/02;C07D235/30;A61K31/41;A61K31/418;A61K31/423;A61K31/428;A61K31/443;A61K31/454;A61K31/470;A61K31/537 |
主分类号 |
A61K31/4439 |
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