发明名称 |
ENZYME DISRUPTION OF BACTERIAL BIOFILMS |
摘要 |
Methods for treating patients in which damaged tissue or an indwelling prosthetic device or catheter has a bacterial biofilm growing thereon, to at least partially disrupt said biofilm, by administering at least one antibacterial enzyme that is lethal or damaging to the biofilm-forming bacteria in an amount that is effective to at least partially disrupt the biofilm upon contact therewith. Methods for prophylactically treating a patient, and methods for disinfecting or sterilizing a surface ex-vivo to remove a biofilm or prevent biofilm growth are also disclosed, as well as implantable articles susceptible to biofilm growth to which a prophylactic coating of an antibacterial enzyme has been applied.
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申请公布号 |
CA2476288(A1) |
申请公布日期 |
2003.10.09 |
申请号 |
CA20032476288 |
申请日期 |
2003.03.26 |
申请人 |
BIOSYNEXUS INCORPORATED |
发明人 |
WALSH, SCOTT;ADAMS WU, JULIE;KOKAI-KUN, JOHN;CHANTURIYA, TATYANA;SHAH, ANJALI;MOND, JAMES |
分类号 |
A01N63/00;A61K38/48;A61L27/54;A61L29/16;(IPC1-7):A61K38/48;A61L2/00;A61L29/04;A61P31/04;A61L29/08;A61L27/14;A61L27/34 |
主分类号 |
A01N63/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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