| 发明名称 |
Modulators of the cholesterol biosynthetic pathway |
| 摘要 |
The present invention relates to methods for modulating the cholesterol biosynthetic pathway. The level of cholesterol in the body is linked to numerous pathological states. The methods of the present invention alter the transcription levels of genes involved in the cholesterol biosynthesis. The methods of the present invention can used for treating diseases mediated by the cholesterol biosynthetic pathway.
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| 申请公布号 |
US2003191110(A1) |
申请公布日期 |
2003.10.09 |
| 申请号 |
US20020286416 |
申请日期 |
2002.11.01 |
| 申请人 |
BOTFIELD MARTYN;MCDONALD FIONA;KRAETZSCHMAR JOERN;LINDENTHAL BERNHARD;KREFT BERTOLD |
发明人 |
BOTFIELD MARTYN;MCDONALD FIONA;KRAETZSCHMAR JOERN;LINDENTHAL BERNHARD;KREFT BERTOLD |
| 分类号 |
C07D277/06;A61K31/439;A61K31/445;A61K31/4523;A61K31/454;A61K31/4545;A61K31/495;A61K31/496;A61K31/506;A61P3/06;A61P25/14;A61P25/28;A61P43/00;C07D205/04;C07D207/16;C07D207/20;C07D209/02;C07D211/26;C07D211/60;C07D211/78;C07D401/06;C07D401/12;C07D405/12;C07D409/12;C07D417/06;C07D471/08;C07D487/08;(IPC1-7):A61K31/553;A61K31/554;A61K31/551;A61K31/55;A61K31/541;A61K31/537;A61K31/519;A61K31/52 |
主分类号 |
C07D277/06 |
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