The present invention relates to processes for producing an optimized pharmacophore for a target protein. The present invention also relates to processes for identifying compounds having an affinity to a target protein. The present invention also relates to processes for designing a ligand for a target protein using the optimized pharmacophore of the present invention. The present invention also provides a computer for use in designing a ligand for a target protein using the optimized pharmacophore of the present invention.
申请公布号
WO03038442(A3)
申请公布日期
2003.10.09
申请号
WO2002US34512
申请日期
2002.10.29
申请人
VERTEX PHARMACEUTICALS INCORPORATED;VAN DRIE, JOHN, H.;PENG, JEFFREY, W.