摘要 |
<p>It is found out that a compound serving as an agonist to ORL-1 receptor also serves as a non-photic entrainment factor and advances the circadian rhythm phase. Thus, it is intended to provide a novel remedy for sleep disturbance such as circadian rhythm sleep disturbance, more specifically, a preventive and/or a remedy for sleep disturbance containing the ORL-1 receptor agonist, and a novel compound useful as the preventive and/or the remedy.</p> |