PROCESS FOR CROSSLINKING POLYPEPTIDES

摘要

A process for crosslinking polypeptides containing tyrosine surrounded by uncharged amino acids having low-molecular side chains by treating such a polypeptide with a phenol oxidase. This crosslinking is catalyzed by phenol oxidases such as tyrosinase and this catalysis is specific for tyrosine surrounded by uncharged amino acids having low-molecular side chains. This process is useful in crosslinking arbitrary polypeptides.