POLYMERIC CHIP FOR IDENTIFYING IONIC POLYMER AND METHOD FOR IDENTIFYING IONIC POLYMER

摘要

PROBLEM TO BE SOLVED: To provide a method for identifying an ionic polymer bonding to an ionic polymer such as a DNA. SOLUTION: The method comprises the following practice. For identifying e.g. a positively charged ionic polymer, another negatively charged ionic polymer is immobilized on a substrate or beads, to which the positively charged ionic polymer is adsorbed. On making the ionic ambience decline rapidly, the resulting adsorbed conjugate is stabilized. But the immobilized ionic polymer with no adsorption becomes unstable in structure. If a marker discriminating between stable and instable structures is marked on the immobilized ionic polymer, it is possible to judge which immobilized ionic polymer adsorbed the ionic polymer intended to identify. COPYRIGHT: (C)2004,JPO