发明名称 Quinolizinones as integrin inhibitors
摘要 The present invention is directed towards novel compounds that are effective inhibitors of integrins, particularly alphaIIbbeta3 or alphav integrins such as alphavbeta3 and alphavbeta5. One embodiment of the present invention comprises a compound of formula (I) or formula (II) or a pharmaceutically acceptable salt, solvate, or metabolic precursor thereof. R1, R2, R3, and R4 are defined herein.
申请公布号 US6630488(B1) 申请公布日期 2003.10.07
申请号 US20010805780 申请日期 2001.03.20
申请人 BIOCHEM PHARMA, INC. 发明人 LAMOTHE SERGE;ZACHARIE BOULOS;ATTARDO GIORGIO;LABRECQUE DENIS;COURCHESNE MARC;FALARDEAU GUY;REJ RABINDRA;ABBOTT SHAUN
分类号 C07D455/02;(IPC1-7):C07D455/02;C07D403/06;A61K31/435;A61K31/496 主分类号 C07D455/02
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