发明名称 Novel process for the preparation of alpha-(2-4-disulfophenyl)-N-tert-butylnitrone and pharmaceutically acceptable salts thereof.
摘要 A process for the preparation of alpha-(2,4-disulfophenyl)-N-tert-butylnitrone diacids and pharmaceutically acceptable salts thereof by the reaction of the corresponding disulfophenyl aldehyde with N-tert-butylhydroxylammonium acetate is disclosed.
申请公布号 ZA200204872(B) 申请公布日期 2003.10.07
申请号 ZA20020004872 申请日期 2002.06.18
申请人 ASTRAZENECA AB;CENTAUR PHARMACEUTICALS, INC. 发明人 JOERGEN BLIXT;JOHN MCGINLEY;JOHN VAJDA;HENRY KRUK;SERGEI POUHOV
分类号 C07C291/04;C07C303/22;C07C303/32;C07C309/46;C07C309/47 主分类号 C07C291/04
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