发明名称 |
1,2,3,4-Tetrahydro-benzofuro[3,2-c]pyridine derivatives |
摘要 |
<p>The present invention concerns the compounds of formula (I), the N-oxides, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein each R1 is independently hydrogen, halogen, C1-6alkyl, nitro, hydroxy or 1-4alkyloxy; Alk is C1-6alkanediyl; n is 1 or 2; D is an optionally substituted mono-, bi- or tricyclic nitrogen containing heterocycle having central 'alpha'2-adrenoceptor antagonist activity. It further relates to their preparation, compositions comprising them and their use as a medicine.</p> |
申请公布号 |
SK283621(B6) |
申请公布日期 |
2003.10.07 |
申请号 |
SK19990000287 |
申请日期 |
1998.04.02 |
申请人 |
JANSSEN PHARMACEUTICA N. V. |
发明人 |
KENNIS LUDO EDMOND JOSEPHINE;LOVE CHRISTOPHER JOHN;BISCHOFF FRANCOIS PAUL |
分类号 |
A61K31/00;A61K31/427;A61K31/435;A61K31/4353;A61K31/4355;A61K31/4375;A61K31/445;A61K31/5025;A61K31/505;A61K31/506;A61K31/519;A61K31/529;A61P1/00;A61P3/00;A61P3/10;A61P9/00;A61P15/00;A61P15/10;A61P25/00;A61P25/02;A61P25/16;A61P25/24;A61P25/28;C07D491/04;C07D491/048;C07D498/04;C07D513/04;C07D519/00;(IPC1-7):C07D491/048 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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