发明名称 FLUORENE DERIVATIVES AS INTEGRIN INHIBITORS
摘要 The invention relates to compounds of formula (I) wherein R<1>, R<2>, R<3>, R<4>, R<5>, m and n have the meaning given in Claim 1, and to their physiologically acceptable salts and solvates, which can be used as integrin inhibitors, especially for the prophylaxis and treatment of blood circulation disorders, thrombosis, myocardial infarction, coronary disorders, arteriosclerosis, osteoporosis, pathological processes which are maintained or propagated through angiogenesis, as well as in tumour therapy.
申请公布号 PL353054(A1) 申请公布日期 2003.10.06
申请号 PL20000353054 申请日期 2000.07.26
申请人 MERCK PATENT GMBH 发明人 STAHLE WOLFGANG;GOODMAN SIMON
分类号 A61K31/4164;A61K31/4184;A61P7/02;A61P9/04;A61P9/10;A61P19/02;A61P19/10;A61P35/00;C07C279/12;C07D233/48;C07D235/30 主分类号 A61K31/4164
代理机构 代理人
主权项
地址