发明名称 IDENTIFICATION OF KINASE INHIBITORS
摘要 The invention concerns the identification of protein kinase inhibitors that preferentially bind to the inactive conformation of a target protein kinase. The inhibitors are identified by locking the target protein kinase in an inactive conformation, and using a covalent tethering approach to identify inhibitors preferentially targeting the inactive conformation.
申请公布号 WO03081210(A2) 申请公布日期 2003.10.02
申请号 WO2003US08725 申请日期 2003.03.20
申请人 SUNESIS PHARMACEUTICALS, INC.;PRESCOTT, JOHN, C.;BRAISTED, ANDREW 发明人 PRESCOTT, JOHN, C.;BRAISTED, ANDREW
分类号 G01N33/566;C12N15/09;C12Q1/48;C40B30/04;G01N33/68 主分类号 G01N33/566
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