发明名称 CELL CYCLE CONTROL COMPOSITION AND ITS USING METHOD
摘要 <p><P>PROBLEM TO BE SOLVED: To provide a cell cycle control composition for controlling the progress of cell cycle of an organism and its using method; a safe and effective method and composition for reversibly inhibiting the progress of cell cycle of an organism; and a technique which can be used in combination with a curing method inhibiting the oncogenesis of an organism. <P>SOLUTION: A method for controlling the cell cycle progress in a cell which is deficient in functional retinoblastoma tumor suppressor protein is provided. In this method, a biologically active, p110RB carboxy-terminal fragment with 56 kDalton is introduced into a cell to be controlled during the period of cell cycle; and while the viability of the cell is maintained, the cell cycle progress of the cell is changed. <P>COPYRIGHT: (C)2004,JPO</p>
申请公布号 JP2003277290(A) 申请公布日期 2003.10.02
申请号 JP20030102318 申请日期 2003.04.04
申请人 UNIV CALIFORNIA 发明人 LEE WEN-HWA;LEE EVA Y-H P;GOODRICH DAVID W;WANG NANG-PING
分类号 C12N5/10;A61K38/00;A61K38/22;A61P35/00;A61P43/00;C07K14/47;C07K14/52;C12N5/00;C12N5/06;C12N15/09;C12P21/02;(IPC1-7):A61K38/22 主分类号 C12N5/10
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