发明名称 |
C-5 Modified indazolylpyrrolotriazines |
摘要 |
The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
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申请公布号 |
US2003186983(A1) |
申请公布日期 |
2003.10.02 |
申请号 |
US20020294281 |
申请日期 |
2002.11.14 |
申请人 |
MASTALERZ HAROLD;ZHANG GUIFEN;TARRANT JAMES G.;VITE GREGORY D. |
发明人 |
MASTALERZ HAROLD;ZHANG GUIFEN;TARRANT JAMES G.;VITE GREGORY D. |
分类号 |
A61K31/53;A61K31/5377;A61K45/00;A61P35/00;A61P43/00;C07D;C07D487/04;(IPC1-7):A61K31/53 |
主分类号 |
A61K31/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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