SUBSTITUTED HETEROARYLALKANOIC ACIDS AND THEIR USE AS ALDOSE REDUCTASE INHIBITORS

摘要

Disclosed are substituted heteroarylalkanoic acids acids of the following formula D-A-C (O)R' where D, A, and R' are defined herein. These compounds are useful in the treatement of chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds and methods of treatment employing the compounds, as well as methods for their synthesis.