COMPOSITION FOR HARD TISSUE AUGMENTATION

摘要

The present invention relates to in-situ crosslinkable compositions for augmenting hard tissue. Said composition comprises first and second precursor components wherein the first precursor component comprises at least two nucleophilic groups and the second precursor component comprises at least two electrophilic groups and wherein the first and second precursor components are selected such that the nucleophilic and electrophilic groups form covalent linkages with each other at the site of application in the body. A preferred use of the compositions of the present invention is in vertebroplasty, thus for augmenting vertebrae of the spine.