| 摘要 |
Disclosed herein are compounds of formula (1): wherein R<1 >is hydroxy or NHSO2R<1A >wherein R<1A >is (C1-8)alkyl, (C3-7)cycloalkyl or {(C1-6)alkyl-(C3-7)cycloalkyl}, which are all optionally substituted from 1 to 3 times with halo, cyano, nitro, O-(C1-6)alkyl, amido, amino or phenyl, or R<1A >is C6 or C10 aryl which is optionally substituted from 1 to 3 times with halo, cyano, nitro, (C1-6)alkyl, O-(C1-6) alkyl, amido, amino or phenyl; R<2 >is (C4-6)cycloalkyl; R<3 >is t-btuyl or (C5-6) cycloalkyl and R<4 >is (C4-6)cycloalkyl; or a pharmaceutically acceptable salt thereof. The compounds are useful as inhibitors of HCV NS3 protease.
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