| 摘要 |
<p>The present invention relates to methods and reagents for [18F]-fluorination, particularly of peptides. The resultant 18F-labelled compounds are useful as radiopharmaceuticals, specifically for use in Positron Emission Tomography (PET). Thus, a compound of formula 18F-(Linker) -SH, such as a compound of formula (IV), (V), or (VI): 18F-(CH2CH2O)n-(CH2)m-SH; (IV); 18F-(CH2)p-SH; (V); may be reacted with an activated peptide as a means for 18F-labelling.</p> |
