| 发明名称 |
COSTIMULATORY MOLECULE AND ITS USE |
| 摘要 |
The invention relates to a novel co-stimulatory pathway mediated by a member of the semaphorin protein family, Sema4A, which is selectively expressed on the surface of dendritic cells. In addition, the invention relates to the use of Sema4A protein and protein derivatives in a method for the identification of immunomodulatory substances and to therapeutic applications making use thereof.
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| 申请公布号 |
WO03080673(A1) |
申请公布日期 |
2003.10.02 |
| 申请号 |
WO2003EP02785 |
申请日期 |
2003.03.18 |
| 申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH;KIKUTANI, HITOSHI;KUMANOGOH, ATSUSHI;BARSOUMIAN, EDWARD, LEON |
发明人 |
KIKUTANI, HITOSHI;KUMANOGOH, ATSUSHI;BARSOUMIAN, EDWARD, LEON |
| 分类号 |
C12N15/09;A61K38/00;A61K39/395;A61P1/04;A61P1/16;A61P3/06;A61P3/10;A61P5/14;A61P7/06;A61P11/06;A61P13/12;A61P17/06;A61P19/02;A61P21/04;A61P25/00;A61P27/02;A61P29/00;A61P31/04;A61P31/10;A61P31/12;A61P31/18;A61P37/02;A61P37/04;A61P37/06;A61P37/08;C07K14/47;C07K14/705;C07K16/18;C07K16/28;C07K19/00;C12Q1/02;(IPC1-7):C07K16/24 |
主分类号 |
C12N15/09 |
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