发明名称 |
PHENANTHRIDINONES AS PARP INHIBITORS |
摘要 |
A compound of the formula (I):whereinring A is a carbocyclic group, R1 is hydrogen or a halogen atom or a lower alkyl group,R2 is a di(lower)alkylamino group or N-containing heterocyclic group, among which the N-containing heterocyclic group may be substituted with one or more substituent(s),Y is an oxygen or sulfur atom, n is an integer from 0 to 2, andm is an integer from 0 to 4,or its prodrug, or their salt.which has poly(adenosine 5'-diphospho-ribose)polymerase inhibiting activity.
|
申请公布号 |
WO03080581(A1) |
申请公布日期 |
2003.10.02 |
申请号 |
WO2003JP03579 |
申请日期 |
2003.03.25 |
申请人 |
FUJISAWA PHARMACEUTICAL CO., LTD.;YAMAMOTO, HIROFUMI;MUKOYOSHI, KOICHIRO;HATTORI, KOUJI |
发明人 |
YAMAMOTO, HIROFUMI;MUKOYOSHI, KOICHIRO;HATTORI, KOUJI |
分类号 |
A61K31/473;A61K31/496;A61K31/5377;A61P1/04;A61P3/10;A61P9/00;A61P9/10;A61P17/16;A61P19/02;A61P19/08;A61P19/10;A61P21/00;A61P21/04;A61P25/00;A61P25/04;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/28;A61P31/04;A61P31/18;A61P35/00;A61P37/00;A61P39/02;A61P43/00;C07D221/12;C07D401/04;C07D401/06;C07D401/12;C07D401/14;C07D409/14;C07D471/04;C07D487/04;(IPC1-7):C07D221/12 |
主分类号 |
A61K31/473 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|