发明名称 METHOD FOR THE PRODUCTION AND THE USE OF MICROPARTICLES AND NANOPARTICLES BY CONSTRUCTIVE MICRONISATION
摘要 The invention relates to a method for producing microparticles and/or nanoparticles of a substance, wherein particles are formed from a molecularly distributed substance which is simultaneously stabilised in a suspension. The substance is dissolved in a solvent system and subsequently a non-solvent for said substance is added whereby said non-solvent can be mixed with the solvent system for said substance. One or several crystal growth inhibitors are added and a rapid merging of solvents and non-solvents takes place. The substance is precipitated by forming a dispersion of particles whose size lies within the micrometer or nanometer range.
申请公布号 WO03080034(A2) 申请公布日期 2003.10.02
申请号 WO2003EP02984 申请日期 2003.03.21
申请人 PHARMATECH GMBH;MUELLER, BERND, W.;RASENACK, NORBERT 发明人 MUELLER, BERND, W.;RASENACK, NORBERT
分类号 A61K9/10;A61K9/00;A61K9/14;A61K9/16;A61K9/19;A61K9/51;A61K9/72 主分类号 A61K9/10
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