发明名称 |
METHOD FOR THE PRODUCTION AND THE USE OF MICROPARTICLES AND NANOPARTICLES BY CONSTRUCTIVE MICRONISATION |
摘要 |
The invention relates to a method for producing microparticles and/or nanoparticles of a substance, wherein particles are formed from a molecularly distributed substance which is simultaneously stabilised in a suspension. The substance is dissolved in a solvent system and subsequently a non-solvent for said substance is added whereby said non-solvent can be mixed with the solvent system for said substance. One or several crystal growth inhibitors are added and a rapid merging of solvents and non-solvents takes place. The substance is precipitated by forming a dispersion of particles whose size lies within the micrometer or nanometer range. |
申请公布号 |
WO03080034(A2) |
申请公布日期 |
2003.10.02 |
申请号 |
WO2003EP02984 |
申请日期 |
2003.03.21 |
申请人 |
PHARMATECH GMBH;MUELLER, BERND, W.;RASENACK, NORBERT |
发明人 |
MUELLER, BERND, W.;RASENACK, NORBERT |
分类号 |
A61K9/10;A61K9/00;A61K9/14;A61K9/16;A61K9/19;A61K9/51;A61K9/72 |
主分类号 |
A61K9/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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