发明名称 PIRAZINO '1 DOLLAR M(1)2 DOLLAR M(1) :1, 6! PYRIDO '3,4-B! INDOLE DERIVATIVES
摘要 Compounds of the general structural formula and use of the compounds and salts and solvates thereof, as therapeutic agents. In particular, the invention relates to compounds that are potent and selective inhibitors of cyclic guanosine 3', 5' monophosphate specific phosphodiesterase (cGMP-specific PDE), in particular PDE5.
申请公布号 WO0200656(A3) 申请公布日期 2003.10.02
申请号 WO2001US15935 申请日期 2001.05.15
申请人 LILLY ICOS LLC;ORME, MARK, W.;SAWYER, JASON, SCOTT;SCHULTZE, LISA, M.;DAUGAN, ALAIN, CLAUDE-MARIE;GELLIBERT, FRANCOISE 发明人 ORME, MARK, W.;SAWYER, JASON, SCOTT;SCHULTZE, LISA, M.;DAUGAN, ALAIN, CLAUDE-MARIE;GELLIBERT, FRANCOISE
分类号 C07D453/02;A61K31/4985;A61K31/5377;A61K31/55;A61P1/00;A61P1/04;A61P1/14;A61P7/02;A61P9/00;A61P9/04;A61P9/08;A61P9/10;A61P9/12;A61P11/00;A61P11/02;A61P11/06;A61P11/08;A61P11/16;A61P13/08;A61P13/12;A61P15/00;A61P15/06;A61P15/08;A61P15/10;A61P19/10;A61P27/06;A61P29/00;A61P35/00;A61P37/08;A61P43/00;C07D471/14;C07D519/00 主分类号 C07D453/02
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