PROCESS FOR PREPARING OPTICALLY ACTIVE BETA-AMINOCARBOXYLIC ACIDS FROM RACEMIC N-ACYLATED BETA-AMINOCARBOXYLIC ACIDS

摘要

A process is described for preparing optically active .beta.-aminocarboxylic acids from racemic N-acylated .beta.-aminocarboxylic acids by enantioselecti ve hydrolysis of the N-acylated .beta.-aminocarboxylic acid in the presence of a hydrolase by way of biocatalyst, wherein the N-acyl substituent of the N- acylated .beta.-aminocarboxylic acid (I) exhibits Structure I in which R1, R 2 are each selected, independently of one another, from H, halogen, alkyl residues, OH, alkoxy residues and aryloxy residues; R3 is selected from halogen, alkoxy residues and aryloxy residues; (II) Structure IIA or IIB or the structure of the corresponding salts or (III) Structure III or the structure of the corresponding salt.