摘要 |
<p>The invention provides a human GPR10 which is associated with the inflammation, respiratory diseases like COPD and asthma, genito-urological diseases, disorders of the peripheral nervous system, hematology diseases, cardiovascular diseases and gastro-intestinal diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of inflammation, respiratory diseases like COPD and asthma, genito-urological diseases, disorders of the peripheral nervous system, hematology diseases, cardiovascular diseases and gastro-intestinal diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of GPR10 as well as pharmaceutical compositions comprising such compounds.</p> |