发明名称 |
Tumor radiosensitization using gene therapy |
摘要 |
The invention provides a method of radiosensitizing a tumor in a subject by contacting the tumor with a cytokine or a nucleic acid molecule encoding a cytokine. The invention also provides a method of radiosensitizing a tumor in a subject by administering, at a site other than the tumor, a cell genetically modified to express a cytokine. The invention further provides a method of reducing the severity of a cancer in a subject by administering a cytokine at the site of the tumor or by immunizing the subject at a site other than the tumor with tumor cells genetically modified to express a cytokine, and treating the tumor with radiotherapy.
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申请公布号 |
US2003185810(A1) |
申请公布日期 |
2003.10.02 |
申请号 |
US20030420278 |
申请日期 |
2003.04.21 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
MCBRIDE WILLIAM H. |
分类号 |
C12N15/09;A61K31/00;A61K38/00;A61K38/19;A61K38/20;A61K39/00;A61K48/00;A61K51/00;A61P35/00;C12N5/10;(IPC1-7):A61K48/00;A61N5/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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