| 发明名称 |
Triamide-substituted heterobicyclic compounds |
| 摘要 |
The invention relates to triamide MTP/ApoB inhibitors of the formula 1 wherein R<1>-R<8 >are as defined in the specification, as well as pharmaceutical compositions and uses thereof, and processes for preparing the compounds. The compounds of the invention are useful for the treatment of obesity and lipid disorders.
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| 申请公布号 |
US2003187053(A1) |
申请公布日期 |
2003.10.02 |
| 申请号 |
US20020177858 |
申请日期 |
2002.06.20 |
| 申请人 |
PFIZER INC. |
发明人 |
BERTINATO PETER;BLIZE ALAN E.;BRONK BRIAN S.;CHENG HENGMIAO;LI JIN;HUATAN HIEP;MASON CLIVE |
| 分类号 |
A61K31/341;A61K31/343;A61K31/397;A61K31/404;A61K31/4045;A61K31/405;A61K31/4439;A61K31/4525;A61K31/4709;A61K31/501;A61K31/5377;A61P3/04;A61P3/06;A61P9/10;A61P43/00;C07D209/42;C07D307/85;C07D401/12;C07D401/14;C07D403/12;C07D405/12;C07D409/12;(IPC1-7):A61K31/405;A61K31/381;A61K31/443;C0749/02;C0745/02;C0743/02;C07D209/18 |
主分类号 |
A61K31/341 |
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