| 发明名称 |
Gene involved in CADASIL, method of diagnosis and therapeutic application |
| 摘要 |
The invention concerns the Notch3 gene and the corresponding protein, which are involved in CADASIL. The invention concerns, in particular, methods for demonstrating mutations in this gene, which are linked to the risk of developing CADASIL. The invention also concerns models and products for treating CADASIL and related diseases.
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| 申请公布号 |
US2003186290(A1) |
申请公布日期 |
2003.10.02 |
| 申请号 |
US20030356625 |
申请日期 |
2003.02.03 |
| 申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) |
发明人 |
TOURNIER-LASSERVE ELISABETH;JOUTEL ANNE;BOUSSER MARIE-GERMAINE;BACH JEAN-FRANCOIS |
| 分类号 |
G01N33/53;A61K31/7088;A61K38/00;A61K39/395;A61K48/00;A61P9/00;A61P25/00;A61P25/06;A61P25/14;C07K14/705;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/12;C12P21/02;C12P21/08;C12Q1/68;(IPC1-7):C12Q1/68;G01N33/567;C07H21/04;C12N5/06 |
主分类号 |
G01N33/53 |
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