FUSED BICYCLIC PYRIDINE DERIVATIVE AS TACHYKININ RECEPTOR ANTAGONIST

摘要

A novel fused bicyclic pyridine derivative represented by the following general formula (1), which has an antagonistic effect on tachykinin receptor s, especially on an NK1 receptor. It is a fused bicyclic pyridine derivative represented by the general formula (1): (1) (wherein rings A and B each represents a benzene ring optionally having one to three substituents (two adjacent substituents may be bonded to each other to form a ring) each independently selected among halogen atoms, optionally substituted C1-6 alkyls, and optionally substituted C1-6 alkoxys; R represents C1-6 alkylsulfonyl, C1-6 alkylcarbonyl, C1-6 alkoxycarbonyl, or formyl; m is 1 or 2; n is 2 or 3; and q is 1 or 2) or a salt of the derivative.