DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH GROWTH HORMONE SECRETAGOGUE RECEPTOR (GHS)

摘要

The invention provides a human GHS which is associated with the cardiovascular diseases, disorders of the peripheral and central nervous system, respiratory diseases like COPD and asthma, hematological diseases, cancer, gastro-intestinal diseases and inflammation. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, disorders of the peripheral and central nervous system, respiratory diseases like COPD and asthma, hematological diseases, cancer, gastro-intestinal diseases and inflammation. The invention also features compounds which bind to and/or activate or inhibit the activity of GHS as well as pharmaceutical compositions comprising such compounds.