MODULATION OF ANGIOGENESIS THROUGH TARGETING OF ARGINYL TRANSFERASE (ATE1)
摘要
The invention provides methods and compositions for modulating angiogenesis in a subject. The methods of modulating angiogenesis in a subject include administering to the subject a modulator of N-terminal arginylation activity. The invention also provides a method of identifying such a modulator and a method of in vitro screening for modulators of N-terminal arginylation activity. Additionally, the invention provides a method of treating an angiogenesis-related disorder.
申请公布号
WO03079999(A2)
申请公布日期
2003.10.02
申请号
WO2003US09061
申请日期
2003.03.21
申请人
CALIFORNIA INSTITUTE OF TECHNOLOGY;KWON, YOUNG, TAE;KASHINA, ANNA, S.;VARSHAVSKY, ALEXANDER
发明人
KWON, YOUNG, TAE;KASHINA, ANNA, S.;VARSHAVSKY, ALEXANDER