摘要 |
A method of treating an Msk-1 and/or ROCK(1 and 2) mediated disease or condition in a mammal comprising administration of an effective amount of a compounds of the formula (I) and physiologically acceptable salts thereof wherein, R>1< is a 5, or 6 membered heterocyclic group selected from group a, b, c or d wherein X>1< is a group selected from N or CR>7< and X>2< is a group selected from O, S or NR>8<; X>3< and X>4< which may be the same or different is a group selected from N or CR>7<; X>5< is a group selected from O, S or NR>8< and X>6< is N or CR>7<; X>7<, X>8< and X>9< may be the same or different and selected from a group N or CR>7<, pharmaceutical compositions, novel compounds and processes for their preparation. |
申请人 |
GLAXO GROUP LIMITED;ALBERTI, MICHAEL, JOHN;GARLAND, STEPHEN;JUNG, DAVID, KENDALL;VEAL, JAMES, MARVIN;WITHERINGTON, JASON |
发明人 |
ALBERTI, MICHAEL, JOHN;GARLAND, STEPHEN;JUNG, DAVID, KENDALL;VEAL, JAMES, MARVIN;WITHERINGTON, JASON |