| 摘要 |
<p>The present invention relates generally to processes for the efficient production optically active 3-substituted lactams of formula (I) [Insert chemical formula here] process, comprising: contacting a compound of formula (II): [Insert chemical formula here] with hydrogen under a suitable pressure in the presence of an iridium complex of the formula (R2)IrL+X- wherein L is a chelating diene, X is a non coordinating anion, and R2 is selected from . [Insert chemical formula here]</p> |
