发明名称 |
Thrombomodulin analogs for pharmaceutical use |
摘要 |
The present invention relates to the design, production and use of analogs of thrombomodulin (TM) that have the ability to enhance the thrombin-mediated activation of protein C but which have a significantly reduced ability to promote activation of thrombin-activatable fibrinolysis inhibitor (TAFI). These analogs are useful in, for example, antithrombotic therapy.
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申请公布号 |
US2003186883(A1) |
申请公布日期 |
2003.10.02 |
申请号 |
US20030438648 |
申请日期 |
2003.05.14 |
申请人 |
SCHERING AKTIENGESELLSCHAFT |
发明人 |
LIGHT DAVID;MORSER MICHAEL JOHN;NAGASHIMA MARIKO |
分类号 |
A61K38/00;A61P7/02;C07K14/705;C07K14/745;(IPC1-7):A61K38/36 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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