| 发明名称 |
ABCG5 AND ABCG8: COMPOSITIONS AND METHODS OF USE |
| 摘要 |
The present invention provides nucleic acids encoding a novel ABC family cholesterol transporter, ABCG8. The herein-disclosed sequences can be used for any of a number of purposes, including for the diagnosis and treatment of cholesterol-associated disorders, including sitosterolemia, and for the identification of molecules that associate with and/or modulate the activity of ABCG8.
|
| 申请公布号 |
WO02081691(A9) |
申请公布日期 |
2003.10.02 |
| 申请号 |
WO2001US43823 |
申请日期 |
2001.11.20 |
| 申请人 |
TULARIK INC.;BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM |
发明人 |
HOBBS, HELEN, H.;SHAN, BEI;BARNES, ROBERT;TIAN, HUI |
| 分类号 |
A61K38/00;C07K14/705;C12N15/12;G01N33/68;G01N33/92;(IPC1-7):C12N15/12;C07K16/28;G01N33/53;A61K45/00 |
主分类号 |
A61K38/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
